Survey of Common Eye Diseases in Laboratory Mouse Strains

Anatomy of the Eye and Common Diseases Affecting the Eye

The human eye is a unique part of the human body that has been described as the window to the human soul. The eye being a complex organ is broadly divided into two segments—anterior and posterior segments. Each of these broad segments has specific disease conditions associated with them. This chapter will extensively describe these various components of the eye and the common disease conditions...

Spontaneous Diseases in Commonly Used Mouse Strains

The absence of mitochondrial DNA diversity among common laboratory inbred mouse strains.

Mitochondrial DNA (mtDNA), which exhibits a maternal inheritance and a high rate of evolution, has been widely used as a genetic marker when analyzing maternal lineage and inferring phylogenetic relationships among species. In this study, mtDNA variations among four classical (BALB/c, C3H, C57BL/6J and DBA/2) and three Chinese (TA2, 615 and T739) inbred strains of laboratory mice were analyzed ...

Corticotherapy in Eye Diseases and Its Complications

Corticosteroids are being rn;;ed in different ophthalmic disorder as anti-inflamatory agent.  A.C.T.H. stimulated the supra renal glands and causes an increase steroid concentration of the blood. Corticosteroids can be used as anti­inflamatory agent locally ar.d systemically.  The new corticom,teroids like prednison, dex­xametason and prednisolon are more effective ( 5 to 10 times) than the o...

Obesity and Eye Diseases

Background: Obesity is a chronic metabolic disease that has become an epidemic today.  Objective: Although the effects of obesity on the body have been well studied, less is known about obesity and eye health. Methods The present article is a review study. The search was performed using keywords of obesity and eye diseases in PubMed, Scopus, Web of Science databases from 2000 to 2021.  Resul...